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KMID : 0383820100680010029
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Tuberculosis and Respiratory Diseases
2010 Volume.68 No. 1 p.29 ~ p.33
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A Case of Fatal Hyperinfective Strongyloidiasis with Acute Respiratory Failure and Intestinal Perforation in Lung Cancer Patient
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Kim Hyeon-Sik
Ma Jeong-Eun
Jeong Yi-Yeong
Kim Ho-Cheol
Lee Jong-Deok
Hwang Young-Sil
Ju Ji-Hyun
Kim Yu-Eun
Yun Eun-You
Lee Gi-Dong
Cho Yu-Ji
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Abstract
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Conclusion: Strongyloides stercoralis is an intestinal nematode that is a parasite to humans. The infecting filariform larvae of S. stercoralis enters the host body via the bloodstream, passes through the lungs, penetrates the alveoli, and then ascends the airway to transit down the esophagus into the small bowel. The infection can persist for decades without causing major symptoms and can elicit eosinophilia of varying magnitudes. Of note, this infection can also develop into a disseminated, often fatal, disease (hyperinfection) in patients receiving immunosuppressive corticosteroids. A 65-year-old man who was receiving corticosteroid therapy for the treatment of spinal stenosis was admitted to the emergency room with complaints of abdominal pain and severe dyspnea. We detected many S. stercoralis larvae in the sputum and in the bronchoalveolar-lavage sample collected by bronchoscopy. Here, we report a fatal case of strongyloidiasis with acute respiratory failure and intestinal perforation. In addition, we provide a brief review of the relevant medical literature.
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KEYWORD
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Strongyloides stercoralis, Respiratory Insufficiency, Intestinal Perforation, Immunosuppression
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